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This is an adaptive process by which the body prevents further muscle and calorie loss. It is speculated, that the body in order to contain this hypermetabolism induces some degree of hypothyroidism by inhibiting deiodination of T4 to T3 by the enzyme 5’-monodeiodinase. During these stressful conditions, hypermetabolism, increased energy expenditure, hyperglycemia, and muscle loss takes place. Euthyroid sick syndrome is seen in conditions of starvation and critical illness such as sepsis, surgery, severe trauma, burns, metabolic disorders, bone marrow transplantation, and malignancy. OverviewĮuthyroid sick syndrome is a thyroid hormone disorder in which the levels of T3 ( triiodothyronine) and/or T4 ( thyroxine) are at abnormal levels, in the setting of a severe underlying illness. Associate Editor(s)-in-Chief: Akshun Kalia M.B.B.S. Risk calculators and risk factors for Euthyroid sick syndrome overviewĮditor-In-Chief: C. Natural History, Complications and PrognosisĮuthyroid sick syndrome overview On the WebĪmerican Roentgen Ray Society Images of Euthyroid sick syndrome overviewĪll Images X-rays Echo & Ultrasound CT Images MRIĮuthyroid sick syndrome overview in the newsīlogs on Euthyroid sick syndrome overviewĭirections to Hospitals Treating Psoriasis Differentiating Euthyroid sick syndrome from other Diseases